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  • Active Ingredient Sertraline
Zoloft is a selective serotonin reuptake inhibitor to treat depression, posttraumatic stress disorder, panic disorder, certain types of social anxiety conditions.
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50 mg
Product name Per Pill Per Pack  
60 pills $0.81 $48.74
90 pills $0.64 $73.11 $57.31
120 pills $0.55 $97.48 $65.89
180 pills $0.46 $146.21 $83.05
270 pills $0.40 $219.32 $108.78
360 pills $0.37 $292.43 $134.50
25 mg
Product name Per Pill Per Pack  
90 pills $0.41 $36.86
120 pills $0.37 $49.15 $43.91
180 pills $0.32 $73.73 $58.01
270 pills $0.29 $110.59 $79.14
360 pills $0.28 $147.46 $100.30
100 mg
Product name Per Pill Per Pack  
30 pills $1.46 $43.82
60 pills $0.99 $87.64 $59.44
90 pills $0.83 $131.45 $75.05
120 pills $0.76 $175.27 $90.66
180 pills $0.68 $262.91 $121.90
270 pills $0.63 $394.36 $168.75
360 pills $0.60 $525.82 $215.60

Product Description

Common use

Sertraline belongs to a class of selective serotonin reuptake inhibitors (SSRIs). This medication is used to treat major depression associated with mood disorders. It is also applied in the treatment of body dysmorphic disorder and anxiety.

Dosage and direction

Take Zoloft by mouth with a glass of water, with or without food. Avoid cutting, crushing or chewing this medicine.
Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor.
It may need time for the medicine to help.
Consult your doctor concerning proper dose for you.


Before taking Sertraline tell your doctor or chemist if you are allergic to it; or if you have other allergies.
Inform your doctor or chemist if you have bipolar confusion, eye, liver or kidney problems.
Aged people can be more sensitive to side effects of the medicine.
During  pregnancy this treatment should be used only in case of strong necessity.
As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine.


Prozac should not be used by pregnant/nursing women or children as well as by the patients having demonstrated a reaction of hypersensitivity to Sertraline.

Possible side effect

The most common side effects are quick and irregular pulse, tremor, anxiety, blurred vision, vomiting, fever, diarrheia, etc.
A very serious allergic reaction occurs very seldom. A majority of  people who use this medicine do not have serious side effects.
Turn to your doctor or pharmacist for more details.
In case you notice the effects not listed here, contact your doctor or pharmacist.

Drug interaction

Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use before taking this medication.
Sertraline can interact with:
* MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide Tranylcypromine, etc.
* Antiarrhythmic drugs: Propafenone, Quinidine, etc
* Serotonin-norepinephrine reuptake inhibitors (SNRIs): Desvenlafaxine, Duloxetine, Milnacipram, Venlafaxine.
* Antipsychotics (also called neuroleptics): Fluphenazine, etc.
* H2-receptor antagonists: Cimetidine, Ranitidine, Famotidine, Nizatidine, etc.
Turn to your doctor or pharmacist for more details.

Missed dose

If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice.


If you think you have used too much of this medicine, seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.


Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from reach of children and pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Type Small Molecule
Accession Number DB01104  (APRD00175, DB08567)
Groups Approved
  • (+)-Sertraline
  • (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
  • (1S,4S)-sertraline
  • cis-(+)-sertraline
  • Sertralina
  • Sertraline
  • Sertralinum
CAS number 79617-96-2
Weight Average: 306.23
Monoisotopic: 305.073804963
Chemical Formula C17H17Cl2N
Protein binding

In vitro protein binding studies indicate that sertraline is highly bound to serum proteins (98%) in the range of 20 to 500 ng/mL [Label], predominantly to albumin and α1-acid glycoprotein [6].


The most common signs and symptoms associated with non-fatal sertraline overdosage were somnolence, vomiting, tachycardia, nausea, dizziness, agitation and tremor. No cases of fatal overdosage with only sertraline have been reported. Other important signs of overdose include bradycardia, bundle branch block, coma, convulsions, delirium, hallucinations, hypertension, hypotension, manic reaction, pancreatitis, QT-interval prolongation, Torsade de Pointes, serotonin syndrome, stupor, and syncope [Label]. Oral LD50 of sertraline in mice and rats are 419 - 548 mg/kg and 1327 - 1591mg/kg, respectively [MSDS].

In a lifetime carcinogenicity studies on mice and rats, there was no significant evidence of sertraline-induced carcinogenic effects despite observable dose-related increases in liver adenomas in male mice receiving sertraline at 10-40 mg/kg and an increase in follicular adenomas of the thyroid in female rats receiving sertraline at 40 mg/kg [Label]. There was an increase in uterine adenocarcinomas in rats receiving sertraline at 10-40 mg/kg, however this effect was not understood to be drug-related [Label]. There were no signs of genotoxicity nor impairment of fertility in bacterial assays and animal studies [Label].

Half life

The elimination half-life of sertraline is approximately 25-26 hours. The elimination half-life of desmethylsertraline is approximately 62-104 hours [Label].

Ordering medications online, you need to make sure they can be delivered to your area. We offer free international shipping, so customers can get quality and affordable treatments, irrespective of the country they live in. We also ship to a range of Tunisia cities:

  • Tunis
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  • Sousse
  • Ettadhamen
  • Kairouan
  • Gabès
  • Bizerte
  • Aryanah
  • Gafsa
  • El Mourouj